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E-Posters - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.03 - EPIDEMIOLOGY & RISK FACTORS P2508 - ESOC25-1067 VASCULAR ENDOTHELIAL GROWTH FACTOR AND ISCHEMIC STROKE RISK: A MENDELIAN RANDOMIZATION STUDY Xiao Zhang 1 , Tao Wang 1 , Liqun Jiao 1 1 Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China Background and Aims: Previous studies have reported controversial relationships between circulating vascular endothelial growth factors (VEGF) and ischemic stroke (IS)